Researchers have just lately discovered and succeeded in synthesizing conolidine, a purely natural compound that reveals guarantee as a potent analgesic agent with a more favorable security profile. Even though the correct system of action remains elusive, it can be presently postulated that conolidine can have various biologic targets. Presently,

This compound was also analyzed for mu-opioid receptor exercise, and like conolidine, was observed to own no action at the site. Utilizing the identical paw injection test, quite a few solutions with increased efficacy were being identified that inhibited the Preliminary ache response, indicating opiate-like action. Presented the several mechanisms